Membranous glomerulonephritis with monoclonal immune deposits and crescents

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Membranous nephropathy with crescents.

Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary to systemic lupus erythematosus, chronic infection, or drugs. Rapid decline in renal function in patients with membranous nephropathy may be due to renal vein thrombosis, malignant hypertension, or an additional superimposed destructive process involving the renal parenchyma. Crescents are r...

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Proliferative glomerulonephritis with monoclonal IgG deposits.

Dysproteinemias that result in monoclonal glomerular deposits of IgG are relatively uncommon. Here, we report the largest series of proliferative glomerulonephritis with monoclonal IgG deposits, a form of renal involvement by monoclonal gammopathy that mimics immune-complex glomerulonephritis. We retrospectively identified 37 patients, most of whom were white (81%), female (62%), or older than ...

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A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits That Showed Predominantly Membranous Features

In 2004, the novel category of monoclonal IgG deposition disease has been proposed and termed "proliferative glomerulonephritis with monoclonal IgG deposits" (PGNMID). This disease is characterized by membranoproliferative glomerulonephritis and staining for a single light-chain isotype and gamma heavy-chain subclass. A 76-year-old male who had monoclonal gammopathy was referred to our hospital...

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Development with Th2-Type Immune Membranous Glomerulonephritis

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Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograft.

BACKGROUND AND OBJECTIVES Proliferative GN with monoclonal IgG deposits (PGNMID) is a newly described entity resembling immune complex GN. Its potential to recur in the allograft is undefined. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The first cases of recurrent PGNMID in the allograft are reported. RESULTS The cohort includes four Caucasians (3 women, 1 man) with a mean age 58.5 years...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2005

ISSN: 1460-2385,0931-0509

DOI: 10.1093/ndt/gfh938