Metabolism of chylomicrons of differing triglyceride composition

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Hepatic uptake of chylomicrons and triglyceride emulsions in rats fed diets of differing fat content.

The hepatic removal of plasma chylomicrons was determined for rats fed the following diets: a) containing no triglyceride, b) regular chow diet with 4.5% of its mass as lipid and, c) a corn oil-supplemented chow with triglyceride accounting for 20% of the mass. The fractional hepatic uptake of either radiolabeled chylomicrons or a triglyceride emulsion was reciprocally related to the amount of ...

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Metabolism of Constituent Lipids of Dog Chylomicrons.

Chylomicrons are the vehicles for that fraction of absorbed lipid transported in intestinal lymph. They contain mainly triglycerides and lesser amounts of phospholipids, cholesterol esters, free cholesterol, and protein. The phospholipids do not have a major role in the transport of newly absorbed fatty acids, but there is evidence that they and, to some extent, the free cholesterol and protein...

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The Lipid Composition of Human Plasma Chylomicrons.

The lipid composition of human chylomicrons has been studied using blood collected from normal male volunteers after ingestion of 200 g of butter fat. The concentration of chylomicrons in the blood samples varied widely among 12 subjects but in each case the following lipids were present : triglycerides, diglycerides (probably the 1,2-isomers), monoglycerides, free and esterified cholesterol, t...

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Metabolism of cholesterol-enriched chylomicrons. Catabolism of triglyceride by lipoprotein lipase of perfused heart and adipose tissues.

The chemical and biochemical properties of cholesterol-enriched and cholesterol-poor chylomicrons from rat lymph have been compared. The enriched particles, prepared from cholesterol-containing lipid dispersions, passed into the duodenum, had four to ten times the cholesteryl ester content of the control chylomicrons but had the same content of total "core" (cholesteryl ester + triglyceride) li...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1964

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)40258-5