MetaMIS: a metagenomic microbial interaction simulator based on microbial community profiles
نویسندگان
چکیده
منابع مشابه
Developing SSU rDNA metagenomic profiles of aquatic microbial communities
Five water samples from three sources, two municipal reservoirs in central North Carolina and Toolik Lake in Alaska, were processed to conduct a comparative survey of microbial small subunit rDNA sequences. Genomic DNA was extracted and amplified by PCR using universal SSU rDNA primers to generate 16S and 18S rDNA clone libraries and 50 clones from each library were sequenced and placed in oper...
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BACKGROUND Microbial life dominates the earth, but many species are difficult or even impossible to study under laboratory conditions. Sequencing DNA directly from the environment, a technique commonly referred to as metagenomics, is an important tool for cataloging microbial life. This culture-independent approach involves collecting samples that include microbes in them, extracting DNA from t...
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As is well known, soil is a complex ecosystem harboring the most prokaryotic biodiversity on the Earth. In recent years, the advent of high-throughput sequencing techniques has greatly facilitated the progress of soil ecological studies. However, how to effectively understand the underlying biological features of large-scale sequencing data is a new challenge. In the present study, we used 33 p...
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Application of massively parallel throughput DNA sequencing technologies to the generation of metagenomic datasets from environmental samples is presently transforming the field of microbiology. Whereas traditional (Sanger-based) DNA sequencing technology imparted a high economic cost on data generation, the development of “next-generation” technologies now make the large-scale generation of se...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2016
ISSN: 1471-2105
DOI: 10.1186/s12859-016-1359-0