Methacholine Challenge Testing in the Diagnosis of Asthma
نویسندگان
چکیده
منابع مشابه
Probability of asthma based on methacholine challenge.
Methacholine inhalation challenge has become an accepted test to determine the presence of airway hyperresponsiveness, a hallmark of asthma. To help physicians interpret the results of a methacholine challenge test in a clinical setting, we analyzed the test data of 1,105 subjects, asthmatics and nonasthmatics. Applying Bayes' theorem, a nomogram was constructed incorporating the prechallenge c...
متن کاملRelationship between Methacholine Challenge Testing and exhaled nitric oxide in adult patients with suspected bronchial asthma.
Usually, hyperresponsiveness to inhaled methacholine is considered closely associated with a diagnosis of bronchial asthma. Recently, it has been clearly pointed out that bronchial hyperreactivity (BHR) is not a constant feature of asthma and that this condition is not always related to airways inflammation. In the present study we evaluated 42 Patients (21 positive and 21 negative for bronchia...
متن کاملAssociation of parental FEF25-75% during a methacholine challenge and children's PC20 and diagnosis of asthma
Background There is evidence that paternal and maternal lung function influence children’s pulmonary function. To date, the most widely used pulmonary function test (PFT) to assess airway responsiveness is the PC20 (concentration of methacholine required to decrease FEV1 by 20%). However, other measures of parental lung function may be better predictors of airway responsiveness or asthma develo...
متن کاملMethacholine challenge testing in Reserve Officer Training Corps cadets.
STUDY OBJECTIVE To determine the prevalence of positive results for methacholine challenge tests in asymptomatic Reserve Officer Training Corps (ROTC) cadets with no history of asthma. DESIGN Prospective, blinded cohort comparison study. SETTING Pulmonary diseases clinic in a US Army tertiary-care medical center. PATIENTS One hundred three college students who were undergoing a physical e...
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ژورنال
عنوان ژورنال: Chest
سال: 2020
ISSN: 0012-3692
DOI: 10.1016/j.chest.2020.04.034