Methodologies to decipher the cell secretome

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

An Integrative Omics Strategy to Assess the Germ Cell Secretome and to Decipher Sertoli-Germ Cell Crosstalk in the Mammalian Testis

Mammalian spermatogenesis, which takes place in complex testicular structures called seminiferous tubules, is a highly specialized process controlled by the integration of juxtacrine, paracrine and endocrine information. Within the seminiferous tubules, the germ cells and Sertoli cells are surrounded by testicular fluid (TF), which probably contains most of the secreted proteins involved in cro...

متن کامل

Methodologies and Perspectives of Proteomics Applied to Filamentous Fungi: From Sample Preparation to Secretome Analysis

Filamentous fungi possess the extraordinary ability to digest complex biomasses and mineralize numerous xenobiotics, as consequence of their aptitude to sensing the environment and regulating their intra and extra cellular proteins, producing drastic changes in proteome and secretome composition. Recent advancement in proteomic technologies offers an exciting opportunity to reveal the fluctuati...

متن کامل

Translating transitions – how to decipher peripheral human B cell development

During the last two decades our understanding of human B cell differentiation has developed considerably. Our understanding of the human B cell compartment has advanced from a point where essentially all assays were based on the presence or not of class-switched antibodies to a level where a substantial diversity is appreciated among the cells involved. Several consecutive transitional stages t...

متن کامل

Argonaute2 regulates the pancreatic {beta}-cell secretome

This research was originally published in Molecular & Cellular Proteomics. Tattikota, S.G. and Sury, M.D. and Rathjen, T. and Wessels, H.H. and Pandey, A.K. and You, X. and Becker, C. and Chen, W. and Selbach, M. and Poy, M.N. Argonaute2 regulates the pancreatic {beta}-cell secretome. Mol Cell Proteomics. 2013; 12: 1214-1225. © 2013 by The American Society for Biochemistry and Molecular Biology...

متن کامل

Micropatterning as a tool to decipher cell morphogenesis and functions.

In situ, cells are highly sensitive to geometrical and mechanical constraints from their microenvironment. These parameters are, however, uncontrolled under classic culture conditions, which are thus highly artefactual. Micro-engineering techniques provide tools to modify the chemical properties of cell culture substrates at sub-cellular scales. These can be used to restrict the location and sh...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

سال: 2013

ISSN: 1570-9639

DOI: 10.1016/j.bbapap.2013.01.022