MHC Process
نویسندگان
چکیده
منابع مشابه
Simulation of Major Histocompatibility Complex (MHC) Structure and Peptide Loading into an MHC Binding Pocket with Teachers’Hands
Molecular understanding of three-dimensional (3D) peptide: MHC models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. The present model aims to simulate MHC molecular structure with the hands and make a profound impression on the students.
متن کاملMHC and MHC-related proteins as pleiotropic signal molecules.
Class I molecules of the major histocompatibility complex (MHC) have been studied primarily for their role in presenting peptide antigens to conventional T lymphocytes. An increasing body of evidence suggests that MHC and newly characterized MHC-related molecules have a much more varied function in the body. Many of these molecules are involved in pleiotropic interactions with other proteins, w...
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Differences among males in immunocompetence can affect resistance to parasites and diseases, and sexual ornaments have been suggested to function as indicators of additive genetic variation in disease resistance, health and condition in the good gene models of sexual selection. In this paper the role of genetic variation in the immune system is discussed as an alternative route to explore wheth...
متن کاملMHC class I multimers
T lymphocytes play a key role in the immune response to both foreign and self peptide antigens, which they recognize in combination with MHC molecules. In the past it has been difficult to analyse objectively the specificity, frequency and intensity of T cell responses. The recent application of fluorescent-labelled MHC class I multimers, however, has provided a powerful experimental approach t...
متن کاملWhat is the MHC?
In the fifty years since the rules of histocompatibility were first established, the major histocompatibility complex (MHC) has become one of the most intensively studied regions of the vertebrate genome. Therefore, it seems rather odd that one of the first questions posed at a recent workshop on MHC evolution was ‘what exactly is the MHC?’ Nevertheless, the question was astute because it encom...
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ژورنال
عنوان ژورنال: Journal of the Fuel Society of Japan
سال: 1969
ISSN: 0369-3775,2185-226X
DOI: 10.3775/jie.48.7_550