Micro-processing events in mRNAs identified by DHPLC analysis

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Micro-processing events in mRNAs identified by DHPLC analysis.

Post-transcriptional processes such as alternative splicing and RNA editing have a huge impact on the diversity of the proteome. Detecting alternatively spliced transcripts is difficult when they are rare. In addition, edited transcripts often differ from the genomic sequence by only a few nucleotides. Denaturing high performance liquid chromatography (DHPLC) is routinely used for single nucleo...

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Micro-processing events in mRNAs identi®ed by DHPLC analysis

Post-transcriptional processes such as alternative splicing and RNA editing have a huge impact on the diversity of the proteome. Detecting alternatively spliced transcripts is dif®cult when they are rare. In addition, edited transcripts often differ from the genomic sequence by only a few nucleotides. Denaturing high performance liquid chromatography (DHPLC) is routinely used for single nucleot...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2002

ISSN: 1362-4962

DOI: 10.1093/nar/gkf516