microRNA-375 inhibits osteogenic differentiation by targeting runt-related transcription factor 2
نویسندگان
چکیده
منابع مشابه
Increased microRNA-93-5p inhibits osteogenic differentiation by targeting bone morphogenetic protein-2
BACKGROUND AND PURPOSE Trauma-induced osteonecrosis of the femoral head (TIONFH) is a major complication of femoral neck fractures. Degeneration and necrosis of subchondral bone can cause collapse, which results in hip joint dysfunction in patients. The destruction of bone metabolism homeostasis is an important factor for osteonecrosis. MicroRNAs (miRNAs) have an important role in regulating os...
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OBJECTIVE To investigate the expression and function of osteogenic genes osterix (OSX) and runt-related transcription factor 2 (RUNX2) in the rat periodontal tissues under orthodontic force for the remodeling of the periodontal tissues. METHODS 24 Wistar rats were randomly divided into 4 groups of orthodontic tooth movements for 1, 3, and 7 days (experimental groups) and control group (withou...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2015
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2015.2477