Microtubule polarities indicate that nucleation and capture of microtubules occurs at cell surfaces in Drosophila.

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Microtubule polarities indicate that nucleation and capture of microtubules occurs at cell surfaces in Drosophila

Hook decoration with pig brain tubulin was used to assess the polarity of microtubules which mainly have 15 protofilaments in the transcellular bundles of late pupal Drosophila wing epidermal cells. The microtubules make end-on contact with cell surfaces. Most microtubules in each bundle exhibited a uniform polarity. They were oriented with their minus ends associated with their hemidesmosomal ...

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This report is concerned with the nucleation and organization of microtubule bundles that assemble after 'conventional' centrosomal microtubule-organizing centres have been lost. The microtubule bundles in question span the lengths of wing epidermal cells. Bundles extend between hemidesmosomes at the apical cuticle-secreting surfaces of cells and basal attachment desmosomes that unite the dorsa...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1989

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.108.4.1445