Microvascular hand surgery for digital ischemia in scleroderma
نویسندگان
چکیده
منابع مشابه
Digital Ischemia in Scleroderma Spectrum of Diseases
Systemic Sclerosis (Scleroderma, SSc) is a disease of unknown etiology characterized by widespread vasculopathy and extracellular matrix deposition leading to fibrosis and autoimmune processes. Digital ischemia (digital ulcers (DUs)) is the hallmark of SSc-related vasculopathy and is characterized by endothelial dysfunction leading to intimal proliferation and thrombosis. It happens frequently ...
متن کاملDigital ulcers and outcomes assessment in scleroderma.
Ischaemic ulcerations of the fingertips are common in SSc and a source of pain and disability. Healing has been demonstrated with intravenous iloprost and two studies with bosentan have demonstrated reduction in the occurrence of new digital ulcers (DUs) over 4-6 months of treatment. Both bosentan studies showed no benefit in healing DU and because of this, net DU burden is no different between...
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Raynaud, digital ulcers and calcinosis are frequent manifestations of patients with systemic sclerosis. Digital ulcers are seen in more than half of the patients with scleroderma. Hospitalizations, ischemic complications and impairment of hand function are frequently observed in patients with digital ulcers, especially if treatment is delayed. Rapid and intensive treatment escalation in patient...
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ABSTRACT Chronic rejection remains a potential long-term consequence of hand composite tissue allotransplantation (CTA). Scleroderma has already been proposed as a model for chronic facial allograft rejection based on potential parallels of observed progression of disease and pathophysiology course. This study proposes a similar model for how chronic rejection may manifest itself in the context...
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One of the main principles in hand surgery is the restitution of sensation in fingers which seems hard or impossible in extensive hand traumas especially in war injuries. In this article transfer of sensory branch of radial nerve to sensory branch of median (in 25 cases) and to sensory branch of ulnar nerve (for the first time in literature and in 12 cases) is reported. Operative technics and r...
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ژورنال
عنوان ژورنال: Journal of Scleroderma and Related Disorders
سال: 2019
ISSN: 2397-1983,2397-1991
DOI: 10.1177/2397198319863565