Microvesicular Caspase-1 Mediates Lymphocyte Apoptosis in Sepsis
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چکیده
منابع مشابه
Microvesicular Caspase-1 Mediates Lymphocyte Apoptosis in Sepsis
OBJECTIVE Immune dysregulation during sepsis is poorly understood, however, lymphocyte apoptosis has been shown to correlate with poor outcomes in septic patients. The inflammasome, a molecular complex which includes caspase-1, is essential to the innate immune response to infection and also important in sepsis induced apoptosis. Our group has recently demonstrated that endotoxin-stimulated mon...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0090968