Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis
نویسندگان
چکیده
منابع مشابه
Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis
Correct tissue architecture is essential for normal physiology, yet there have been few attempts to recreate tissues using micro-patterning. We have used polymer brush micro-engineering to generate a stratified micro-epidermis with fewer than 10 human keratinocytes. Epidermal stem cells are captured on 100 μm diameter circular collagen-coated disks. Within 24 h they assemble a stratified micro-...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2012
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2012.04.009