miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1
نویسندگان
چکیده
منابع مشابه
miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1
Osteosarcoma is the most common type of bone cancer in children and adolescents. Impaired differentiation of osteoblast cells is a distinguishing feature of this aggressive disease. As improvements in survival outcomes have largely plateaued, better understanding of the bone differentiation program may provide new treatment approaches. The miRNA cluster miR-23a~27a~24-2, particularly miR-23a, h...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2015
ISSN: 1664-8021
DOI: 10.3389/fgene.2015.00233