Mitochondria and Tumor Progression in Ulcerative Colitis

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Re: Mitochondria and tumor progression in ulcerative colitis.

We read with interest the paper from Ussakli et al., which concludes that cytochrome c oxidase (CCO) loss precedes tumor progression in ulcerative colitis (UC) and may be a biomarker in UC cancer progression (1). They suggest that loss of CCO represents a reduction of the number of mitochondria in preneoplasia; in cancer, COX expression is maintained due to an increase in the number of mitochon...

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ژورنال

عنوان ژورنال: JNCI: Journal of the National Cancer Institute

سال: 2013

ISSN: 1460-2105,0027-8874

DOI: 10.1093/jnci/djt167