Mitotic control in the absence of cdc25 mitotic inducer in fission yeast
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چکیده
منابع مشابه
Mitotic control in the absence of cdc25 mitotic inducer in fission yeast.
Fission yeast cells tolerate the total absence of the cdc25 mitotic inducer in two cases, either in cdc2-3w or in wee1 genetic backgrounds. In the cdc2-3w cdc25Delta double mutant, the rate-limiting step leading to mitosis is reaching a critical size. However, the size control of this mutant operates in late G2, which is different from wild-type (WT) cells. This fact suggests that in WT the rat...
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Entry into mitosis during the somatic cell cycle is regulated in response to signals that monitor the completion of DNA replication, the integrity of the nuclear genome, and, possibly, the increase in cellular mass during the cell cycle. It has been postulated that the operation of this cell cycle control involves the gradual accumulation of rate-limiting mitotic inducers, which trigger nuclear...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 1999
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.112.7.1085