Mixed Lymphocyte Culture Determinants, Measles Infection and Multiple Sclerosis
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چکیده
منابع مشابه
Mixed lymphocyte culture and graft rejection.
while in the midst of a rejection epiria. The degree of specilk reactivity icnts posttransplant nephrectomy or, 'he reactions of peripheral leukocytes ive depletion of cells directed against · example, patient 2 (HL-A2, 28,17, lining (HL-A2, 28;14, 27) was unJd toward targets bearing (HL-AI, , the phenotypes (I-IL-A 2, W32; 8, ). Similarly patient 4 (HL-A 9, 11; · with (HL-A 2, 11 ;W5, W15) de1...
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Four families with C2 deficiency were studied. Among eight HL-A haplotypes involved with C2 deficiency, five were HL-A 10,W18. Three homozygotes for C2 deficiency from different families were mutually nonreactive in mixed lymphocyte cultures (MLC) and the heterozygotes from the fourth family failed to react to the homozygous cells. It appeared that identical MLC determinants were associated ...
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Lymphocyte function in rheumatoid arthritis has been assessed by the mixed lymphocyte culture assay. In contrast to previous studies, no difference was found between lymphocytes from healthy volunteers and patients with rheumatoid arthritis. An occasional patient's lymphocytes failed to respond on a given day, but were normal on restudy. All 44 arthritic patient's lymphocytes underwent blast tr...
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Cellular responses in vitro to H-2D region histocompatibility antigens were demonstrated to be under the genetic control of two or three (P = 0.013) independently segregating loci. The H-2 region itself accounts for one of these loci, however, its activity appears to be dependent upon an association with other non-H-2-associated genetic information. The ability to stimulate a response and to re...
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T cells alloactivated in 5-d MLC with an HLA-DR-different stimulator acquire the capacity of stimulating the autologous mixed lymphocyte response (AMLR). We have demonstrated that activation of AMLR by allosensitized T cells is determined by the expression of the idiotype receptor for the stimulating HLA-DR alloantigen. This has been shown in experiments in which purified, OKT-3-positive T cell...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1974
ISSN: 0035-9157
DOI: 10.1177/003591577406701119