Model-based analysis of non-specific binding for background correction of high-density oligonucleotide microarrays
نویسندگان
چکیده
منابع مشابه
Model-based analysis of non-specific binding for background correction of high-density oligonucleotide microarrays
MOTIVATION High-density DNA microarrays provide us with useful tools for analyzing DNA and RNA comprehensively. However, the background signal caused by the non-specific binding (NSB) between probe and target makes it difficult to obtain accurate measurements. To remove the background signal, there is a set of background probes on Affymetrix Exon arrays to represent the amount of non-specific s...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2008
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btn570