Modeling Resilience to Damage in Multiple Sclerosis: Plasticity Meets Connectivity
نویسندگان
چکیده
منابع مشابه
The path to damage in multiple sclerosis.
For several decades students of multiple sclerosis (MS) have generally accepted the cause of the MS lesion as being entirely T cell mediated. More recently, however, numerous reports of studies of the animal model, experimental allergic encephalomyelitis (EAE), and detailed analysis of the pathology of MS have indicated that the events involved in the MS lesion may be more complicated. In this ...
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I n recent years, enormous strides have been made in increasing the range and efficacy of disease-modifying drugs available for the treatment of multiple sclerosis (MS) in its early and remitting stages, and more continue to emerge. Another equally important concept of successful treatment of MS is neurorehabilitation, which must be pursued alongside these medications. Key factors that contribu...
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Development of disaggregate models for estimating different property damage collision type frequencies in urban intersections has rarely been studied, particularly in Iran. It seems very little research work being implemented for studying the effect factors on collision type frequency at intersections. The main objective of this paper is to develop suitable statistical models to predict types o...
متن کاملAnatomical Connectivity Mapping – Measuring connectivity changes in Multiple Sclerosis
Introduction Anatomical Connectivity Mapping (ACM) based on diffusion MRI generates a scalar map that reflects the connectivity of each voxel with the rest of the brain [1, 2]. The value of an ACM voxel reflects white mater integrity both locally and globally and the ACM is therefore able to reveal effects not seen with traditional diffusion maps such as Mean Diffusivity (MD) or Fractional Anis...
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BACKGROUND The cerebellum is of potential interest for understanding adaptive responses in motor control in patients with multiple sclerosis because of the high intrinsic synaptic plasticity of this brain region. OBJECTIVE To assess the relative roles of interactions between the neocortex and the cerebellum using measures of functional connectivity. METHODS A role for altered neocortical-ce...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms21010143