Modelling of microbial polyhydroxyalkanoate surface binding protein PhaP for rational mutagenesis
نویسندگان
چکیده
منابع مشابه
Modelling of microbial polyhydroxyalkanoate surface binding protein PhaP for rational mutagenesis
Phasins are unusual amphiphilic proteins that bind to microbial polyhydroxyalkanoate (PHA) granules in nature and show great potential for various applications in biotechnology and medicine. Despite their remarkable diversity, only the crystal structure of PhaPAh from Aeromonas hydrophila has been solved to date. Based on the structure of PhaPAh , homology models of PhaPAz from Azotobacter sp. ...
متن کاملStructural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila
Phasins or PhaPs are a group of amphiphilic proteins that are found attached to the surface of microbial polyhydroxyalkanoate (PHA) granules. They have both structural and regulatory functions and can affect intracellular PHA accumulation and mediate protein folding. The molecular basis for the diverse functions of the PhaPs has not been fully understood due to the lack of the structural knowle...
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Polyhydroxyalkanoate (PHA) inclusions are polymeric storage inclusions formed in some bacterial species when carbon levels are high but levels of another essential nutrient, such as nitrogen, are low. Though much is known about PHA synthesis, little is known about inclusion structure. In this study, atomic force microscopy (AFM) was employed to elucidate the structure of PHA inclusions at the n...
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ژورنال
عنوان ژورنال: Microbial Biotechnology
سال: 2017
ISSN: 1751-7915,1751-7915
DOI: 10.1111/1751-7915.12820