Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles
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چکیده
منابع مشابه
Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles.
Increased stiffness of Schlemm's canal endothelial cells (SC cells) is a major contributing factor to the increased pressure characteristic of primary open-angle glaucoma. New treatments for glaucoma are being developed using actin depolymerizers and rho kinase inhibitors to address this increased stiffness. However, these agents have off-target effects and are not as potent as had been hoped. ...
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part A
سال: 2018
ISSN: 1549-3296,1552-4965
DOI: 10.1002/jbm.a.36376