Molecular Characteristics of Mantle Cell Lymphoma Presenting With Clonal Plasma Cell Component
نویسندگان
چکیده
منابع مشابه
Mantle Cell Lymphoma with Multiple Lymphomatous Polyposis Presenting With Intussusceptions
Mantle cell lymphoma is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. The gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. Multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...
متن کاملmantle cell lymphoma with multiple lymphomatous polyposis presenting with intussusceptions
mantle cell lymphoma is an aggressive type of b-cell non-hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. the gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...
متن کاملA case of mantle cell lymphoma presenting with ascites
Ascites with the finding of peritoneal carcinomatosis is considered an unusual presentation for mantle cell lymphoma (MCL) and has been rarely described in literature. This case reflects the importance of cytological analysis of peritoneal fluid in a patient with intractable ascites not contributing from other comorbidities. In the event a bone marrow (BM) analysis cannot be made, this may serv...
متن کاملMantle Cell Lymphoma Presenting with Acute Bilateral Ophthalmoplegia
A 72-year-old woman presented with acute onset of double vision, bilateral complete blepharoptosis, and nearly complete ophthalmoplegia. Orbital and brain magnetic resonance imaging were normal. Further investigation revealed bicytopenia with hepatosplenomegaly. Liver biopsy revealed mantle cell lymphoma. Cytology later showed the presence of mantle cells in cerebrospinal fluid analysis. Her op...
متن کاملMolecular pathogenesis of mantle cell lymphoma.
Mantle cell lymphoma is a B cell malignancy in which constitutive dysregulation of cyclin D1 and the cell cycle, disruption of DNA damage response pathways, and activation of cell survival mechanisms contribute to oncogenesis. A small number of tumors lack cyclin D1 overexpression, suggesting that its dysregulation is always not required for tumor initiation. Some cases have hypermutated IGHV a...
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ژورنال
عنوان ژورنال: American Journal of Surgical Pathology
سال: 2011
ISSN: 0147-5185
DOI: 10.1097/pas.0b013e3182049a9c