Molecular Determinants of Ebola Virus Virulence in Mice
نویسندگان
چکیده
منابع مشابه
Molecular Determinants of Ebola Virus Virulence in Mice
Zaire ebolavirus (ZEBOV) causes severe hemorrhagic fever in humans and nonhuman primates, with fatality rates in humans of up to 90%. The molecular basis for the extreme virulence of ZEBOV remains elusive. While adult mice resist ZEBOV infection, the Mayinga strain of the virus has been adapted to cause lethal infection in these animals. To understand the pathogenesis underlying the extreme vir...
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ژورنال
عنوان ژورنال: PLoS Pathogens
سال: 2006
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.0020073