Molecular Dynamics Simulation of Saposin C-Membrane Binding
نویسندگان
چکیده
منابع مشابه
Molecular Dynamics Simulation of Saposin C-Membrane Binding
To understand the mechanism of Saposin C-membrane binding at low pH, several molecular dynamics (MD) simulations of saposin C with 1,2-dioleoyl-sn-glycero-3-phosphatidylserine (DOPS 18; 1) or modified DOPS were performed in the default charge states at neutral pH or, based on the pKa calculations, with some protonated acidic residues to approximate low pH conditions. It was found that the elect...
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ژورنال
عنوان ژورنال: The Open Structural Biology Journal
سال: 2008
ISSN: 1874-1991
DOI: 10.2174/1874199100802010021