Molecular Features of the V1–V4 Coding Region of Sexually Transmitted Human Immunodeficiency Virus Type 1
نویسندگان
چکیده
منابع مشابه
Resistance mechanism of human immunodeficiency virus type-1 protease to inhibitors: A molecular dynamic approach
Human immunodeficiency virus type 1 (HIV-1) protease inhibitors comprise an important class of drugs used in HIV treatments. However, mutations of protease genes accelerated by low fidelity of reverse transcriptase yield drug resistant mutants of reduced affinities for the inhibitors. This problem is considered to be a serious barrier against HIV treatment for the foreseeable future. In this st...
متن کاملHuman immunodeficiency virus (HIV) & sexually transmitted diseases (STDs).
Among various factors associated with the sexual transmission of HIV, sexually transmitted diseases (STDs) seem to contribute significantly. Hence, the efforts for prevention and control of HIV have to rely largely on STD control measures. In the developing countries, both prevalence and incidence of STDs are very high. STDs impact women's health adversely for a variety of reasons such as more ...
متن کاملThe Molecular Epidemiology of Human Immunodeficiency Virus-Type 1
Centre for HIV Research, Institute of Cell, Animal and Population Biology, and Department of Medical Microbiology, University of Edinburgh, Waddington Building, West Mains Road, Edinburgh, EH9 3JN Scotland: Department of Public Health Medicine, Royal Free Hospital, London NW3, England; Infectious Diseases Unit, City Hospital, Edinburgh, Scotland; King’s Cross Hospital, Dundee, Scot/and; Ruchill...
متن کاملMolecular biology of the human immunodeficiency virus type 1.
The immunodeficiency virus type 1 is a complex retrovirus. In addition to genes that specify the proteins of the virus particle and the replicative enzymes common to all retroviruses, HIV-1 specifies at least six additional proteins that regulate the virus life cycle. Two of these regulatory genes, tat and rev, specify proteins essential for replication. These proteins bind to specific sequence...
متن کاملQuantification Analysis of Dot Blot Assays for Human Immunodeficiency Virus Type 1 and 2 Antibodies
Objective Dot Blot (DB) assay provides highly specific results, but usually not reliable for quantification of antibody production. The need for a more objective DB assay to provide a better definition of the immune status, against HIV antigens, promoted this study to be done to develop a quantitative DB assay. Material and Methods Dot blot (DB) strips for antibodies directed to human immuno...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2017
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jix184