Molecular genotyping for RHD: What (not) to do?

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

invasive aspergillosis (ia) are a major complication in immunocompromized patients where can be serious and rapidly fatal. early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. but despite many efforts to develop detection methods, the diagnosis of ia still remains challenging and current conventional methods are limited for adequate diagno...

Polyposis syndromes– what to do when genotyping seems not informative

Multiple adenomatous polyposis As a routine, we check to see if both sequencing and MLPA has been complete for APC, and full sequencing for MYH (though the return outside the three common mutations is low in our ethnic mix). On at least one occasion, a change in the MLPA kit by Holland Inc lead to identification of an important deletion as the probes changed in the MLPA kit. So recollecting blo...

Do We Know What We Do not Know? A Response to Celine Bonnet

What to Do What Not to Do Advice for Relatives