Molecular Mechanism of General Anesthesia

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Molecular mechanisms of general anesthesia

General anesthetics produce a widespread neurodepression in the central nervous system by enhancing inhibitory neurotransmission and reducing excitatory neurotransmission. However, the action mechanisms of general anesthetics are not completely understood. Moreover, the general anesthetic state comprises multiple components (amnesia, unconsciousness, analgesia, and immobility), each of which is...

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Mechanisms of general anesthesia.

Although general anesthetics are often said to be nonspecific agents, it is likely that they act at a much more restricted set of target sites than commonly believed. The traditional view has been that the primary targets are lipid portions of nerve membranes, but recent evidence shows that the effects on lipid bilayers of clinically relevant levels of anesthetics are very small. Effects on mos...

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ژورنال

عنوان ژورنال: Experimed

سال: 2020

ISSN: 2667-5846

DOI: 10.26650/experimed.2020.824840