Molecular mechanisms of cellular mechanosensing
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Cellular Mechanosensing
Mechanical forces direct a host of cellular and tissue processes. Although much emphasis has been placed on cell-adhesion complexes as force sensors, the forces must nevertheless be transmitted through the cortical cytoskeleton. Yet how the actin cortex senses and transmits forces and how cytoskeletal proteins interact in response to the forces is poorly understood. Here, by combining molecular...
متن کاملO14: Cellular and Molecular Mechanisms of Spinal Cord Trauma
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملo14: cellular and molecular mechanisms of spinal cord trauma
the prevalence of spinal cord injury (sci) is about 2.5 million in the worldwide and more than 130,000 new injuries reported each year. regeneration in the cns versus the pns is very different from the other tissues and many factors can prevent regeneration in pns and specially cns. previous researches demonstrated that regeneration of cns can inhibit by inhibitory molecules and glial scar. the...
متن کاملBiopolymer Networks and Cellular Mechanosensing
Cells and tissues are mechanical as well as biochemical machines, and cellular response to mechanical cues can have as large an influence on structure and function as chemical signals. The mechanical properties of cells are largely determined by networks of semiflexible polymers forming the cytoskeleton, which has viscoelastic properties that differ in important ways from the viscoelasticity of...
متن کاملMolecular mechanisms of cellular mechanicsw
Mechanical forces play an essential role in cellular processes as input, output, and signals. Various protein complexes in the cell are designed to handle, transform and use such forces. For instance, proteins of muscle and the extracellular matrix can withstand considerable stretching forces, hearing-related and mechanosensory proteins can transform weak mechanical stimuli into electrical sign...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Materials
سال: 2013
ISSN: 1476-1122,1476-4660
DOI: 10.1038/nmat3772