Mono-substitution of symmetric diesters: selectivity of Mycobacterium smegmatis acyltransferase variants
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چکیده
منابع مشابه
MICROBIAL TRANSFORMATION OF CHOLESTEROL BY MYCOBACTERIUM SMEGMATIS
Mycobacterium smegmatis PTCC 1307 (CIP 73.26) was used as a microbial agent to produce androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione, two useful precursors in the synthesis of steroid drugs. The side chain of cholesterol, as the substrate, was selectively cleaved in the presence of five enzyme inhibitors. An intermediate structure with intact side chain, cholest-4-ene-3-one, ...
متن کاملBoronic acid mono- and diesters of the aldopentoses.
The four aldopentoses ribose, arabinose, xylose, and lyxose were evaluated to test their suitability as linear linkers for the formation of intrinsically chiral covalent organic boronic ester networks. Based on X-ray crystal structures of the reaction products with phenylboronic acid, arabinose and xylose formed boronic acid diesters. Lyxose and ribose formed monoesters under the conditions emp...
متن کاملmicrobial transformation of cholesterol by mycobacterium smegmatis
mycobacterium smegmatis ptcc 1307 (cip 73.26) was used as a microbial agent to produce androsta-1,4-diene-3,17-dione (add) and androst-4-ene-3,17-dione, two useful precursors in the synthesis of steroid drugs. the side chain of cholesterol, as the substrate, was selectively cleaved in the presence of five enzyme inhibitors. an intermediate structure with intact side chain, cholest-4-ene-3-one, ...
متن کاملTranscriptome Landscape of Mycobacterium smegmatis
The non-pathogenic bacterium Mycobacterium smegmatis mc2155 has been widely used as a model organism in mycobacterial research, yet a detailed study about its transcription landscape remains to be established. Here we report the transcriptome, expression profiles and transcriptional structures through growth-phase-dependent RNA sequencing (RNA-seq) as well as other related experiments. We found...
متن کاملTrehalose synthase of Mycobacterium smegmatis
Yuan T. Pan, Vineetha Koroth Edavana, William J. Jourdian, Rick Edmondson, J. David Carroll, Irena Pastuszak and Alan D. Elbein Department of Biochemistry and Molecular Biology and Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Departments of Biological Chemistry and Internal Medicine, University of Michigan Medical Center, Ann Arbo...
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ژورنال
عنوان ژورنال: Catalysis Science & Technology
سال: 2019
ISSN: 2044-4753,2044-4761
DOI: 10.1039/c9cy01181a