Monosialotetrahexosylganglioside Sodium Promotes the Cortical Neurogenesis in Traumatic Brain Injury Rats

To explore the effect of monosialotetrahexosylganglioside sodium on cortical neurogenesis in traumatic brain injury rats. Thirty Sprague–Dawley rats were randomly divided into control group, saline group and group. The model was prepared with hydraulic controllable device received sham operation. levels oxidative stress, nerve damage, new born neurons, learning memory capabilities assessed serum malondialdehyde superoxide dismutase levels, neurofilament light level terminal deoxynucleotidyl transferase dUTP nick end labeling, neuronal nuclear protein/ bromodeoxyuridine cells Morris water maze respectively. Compared stress significantly increased, damage obvious, number neurons ability decreased other two groups. normal lower, reduced, increases more obviously decline reduced Monosialotetrahexosylganglioside can reduce level, protect from promote cortex improvement cognitive functions such as