Motor and Cognitive Deficits due to Permanent Cerebral Hypoperfusion/ischemia Improve by Pomegranate Seed Extract in Rats

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Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia

Objective: Estrogen deficit following menopause results in cognitive behaviors impairment. Severity of these impairments in menopause women suffer with cerebral hypo perfusion/ischemia (HI) cause the brain damage and neuronal death. This study aimed to evaluate the effects of pomegranate seed extract (PGSE) on avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO...

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Improving active and passive avoidance memories deficits due to permanent cerebral ischemia by pomegranate seed extract in female rats.

BACKGROUND This study aimed to evaluate the effect of two weeks oral administration of pomegranate seed extract (PGSE) on active and passive avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO) to induce permanent cerebral ischemia in adult female rats. METHODS Seventy adult female Wistar rats (250 ± 20 g) were used. Animals were divided randomly into seven g...

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Pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia

OBJECTIVES Estrogen deficit following menopause results in cognitive behaviors impairment. This study aimed to evaluate the effects of pomegranate seed extract (PGSE) on avoidance memories after permanent bilateral common carotid arteries occlusion (2CCAO) in ovariectomized (OVX) rats. MATERIALS AND METHODS Adult female Wistar rats were divided randomly into eight groups with 8 rats in each g...

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Improvement in Memory and Brain Long-term Potentiation Deficits Due to Permanent Hypoperfusion/Ischemia by Grape Seed Extract in Rats

  Objective(s): Cerebral hypoperfusion/ischemia (CHI) is a neurological disease where impaired hippocampus electrical activity and cognition caused by a serial pathophysiological events. This study aimed to evaluate the effects of chronic oral administration of grape seed extract (GSE) on passive avoidance memory and long-term potentiation (LTP) after permanent bilateral common carotid arteries...

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pomegranate seed hydroalcoholic extract improves memory deficits in ovariectomized rats with permanent cerebral hypoperfusion /ischemia

objective: estrogen deficit following menopause results in cognitive behaviors impairment. severity of these impairments in menopause women suffer with cerebral hypo perfusion/ischemia (hi) cause the brain damage and neuronal death. this study aimed to evaluate the effects of pomegranate seed extract (pgse) on avoidance memories after permanent bilateral common carotid arteries occlusion (2ccao...

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ژورنال

عنوان ژورنال: Pakistan Journal of Biological Sciences

سال: 2014

ISSN: 1028-8880

DOI: 10.3923/pjbs.2014.991.998