MST1-JNK promotes apoptosis via caspase-dependent and independent pathways
نویسندگان
چکیده
منابع مشابه
Econazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
متن کاملEconazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways
Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that EN inhibited the proliferation of MCF-7 cells in a time- and dose-dependent manner by MTT method ...
متن کاملUVB-induced apoptosis of human dendritic cells: contribution by caspase-dependent and caspase-independent pathways.
Dendritic cells (DCs) play a central role in the initiation and regulation of the immune response. The modalities by which DCs are committed to undergo apoptosis are poorly defined. Here it is shown that, unlike death receptor ligands, UVB radiation triggers apoptosis of human DCs very efficiently. UVB exposure is followed by the activation of caspases 8, 9, and 3, by the loss of mitochondrial ...
متن کاملLeptospira interrogans induces apoptosis in macrophages via caspase-8- and caspase-3-dependent pathways.
Apoptosis of host cells plays an important role in modulating the pathogenesis of many infectious diseases. It has been reported that Leptospira interrogans, the causal agent of leptospirosis, induces apoptosis in macrophages and hepatocytes. However, the molecular mechanisms responsible for host cell death remained largely unknown. Here we demonstrate that L. interrogans induced apoptosis in a...
متن کاملeconazole nitrate induces apoptosis in mcf-7 cells via mitochondrial and caspase pathways
econazole nitrate (en), a synthetic compound, is now in use as a routine antifungal drug. en was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. in this research, the apoptosis-inducing effect of en on mcf-7 cells was investigated. the results showed that en inhibited the proliferation of mcf-7 cells in a time- and dose-dependent manner by mtt method ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes to Cells
سال: 2001
ISSN: 1356-9597
DOI: 10.1046/j.1365-2443.2001.00439.x