Multi-patient study for coronary vulnerable plaque model comparisons: 2D/3D and fluid–structure interaction simulations
نویسندگان
چکیده
منابع مشابه
[From vulnerable plaque to vulnerable patient].
Atherosclerotic plaque instability is directly involved in triggering acute coronary syndromes, including unstable angina, acute myocardial infarction, and sudden coronary death. Different and not completely unknown mechanisms are involved in the pathogenesis of the destabilisation of the vulnerable plaque; currently three mechanisms are considered to play a causal role in this process: emboliz...
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A therosclerosis is the most common form of vascular disease and constitutes the major cause of death, with 17.5 million related deaths annually (31% of global mortality). Atherosclerotic plaque represents the hallmark lesion of atherosclerosis. Most, but not all, acute cardiac events occur in the context of plaque-related thrombus formation, with the remainder associated with primary cardiomyo...
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Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease. For this reason, screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine. Necropsy studies have described histopathological changes associated with the development of acute coronary events. In this regard, thin-cap fib...
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The term 'vulnerable plaque' is used to refer to the lesions that are prone to rupture and may cause life-threatening events like acute coronary syndrome or stroke. The study of the vulnerable plaque phenotype and its detection has attracted increasing interest over the past decades. During this time, there have been some remarkable transitions in the paradigm on methods to identify patients at...
متن کاملBiomechanical factors in coronary vulnerable plaque risk of rupture: intravascular ultrasound-based patient-specific fluid-structure interaction studies.
OBJECTIVES The aim of this study was to elucidate the mechanisms and underlying biomechanical factors that may play a role in the risk of rupture of vulnerable plaques (VPs) by studying patient-based geometries of coronary arteries reconstructed from intravascular ultrasound (IVUS) imaging utilizing fluid-structure interaction (FSI) numerical simulations. BACKGROUND According to recent estima...
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ژورنال
عنوان ژورنال: Biomechanics and Modeling in Mechanobiology
سال: 2021
ISSN: 1617-7959,1617-7940
DOI: 10.1007/s10237-021-01450-8