Multi-scale modeling of chemo-mechanical coupling in muscle contraction and applications to cardiac modeling
نویسندگان
چکیده
منابع مشابه
Chemo-mechanical model for skeletal muscle contraction
Generation of force in skeletal muscle tissue depends on both chemical and mechanical phenomena. In this work, considering the kinetics of cross bridges, a one dimensional model has been proposed for predicting the isometric force according to the intracellular calcium ion distribution. Introduction The different ways of skeletal muscle activation lead to the formation of cross bridges (XB) acc...
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Department of Bioengineering, UCSD, La Jolla, CA Department of Mathematics, UCSD, La Jolla, CA Department of Chemistry and Biochemistry, Department of Pharmacology, Howard Hughes Medical Institute, UCSD, La Jolla, CA National Biomedical Computation Resource, UCSD, La Jolla, CA National Center for Microscopic and Imaging Research, UCSD, CA Department of Medicine, UCSD, La Jolla, CA Department of...
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Wound healing is a synchronized cascade of chemical, biological, and mechanical phenomena, which act in concert to restore the damaged tissue. An imbalance between these events can induce painful scarring. Despite intense efforts to decipher the mechanisms of wound healing, the role of mechanics remains poorly understood. Here, we establish a computational systems biology model to identify the ...
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ژورنال
عنوان ژورنال: BIO Web of Conferences
سال: 2016
ISSN: 2117-4458
DOI: 10.1051/bioconf/20160602003