Naltrexone Extended-Release Plus Bupropion Extended-Release for Treatment of Obesity
نویسندگان
چکیده
منابع مشابه
Extended-release bupropion induced grand mal seizures.
Bupropion hydrochloride is currently available in three formulations: immediate-release, sustained-release, and extended-release (ER). Several published reports exist concerning bupropion's history of inducing seizures in both the immediate- and sustained-release formulations. Although the potential of the ER formulation for causing seizures is noted in the drug's prescribing information, there...
متن کاملNaltrexone/Bupropion extended release‐induced weight loss is independent of nausea in subjects without diabetes†
Naltrexone/bupropion extended release (NB) is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of ≥30 or ≥27 kg m(-2) and ≥1 weight-related comorbidity (e.g. hypertension, type 2 diabetes and dyslipidaemia). In phase 3 clinical studies, nausea occurred in significantly higher proportions of ...
متن کاملMorphine sulfate and naltrexone hydrochloride extended-release capsules: naltrexone release, pharmacodynamics, and tolerability.
BACKGROUND Morphine sulfate and naltrexone hydrochloride extended-release capsules (EMBEDA, King Pharmaceuticals, Inc., Bristol, TN), indicated for management of chronic, moderate-to-severe pain, contain pellets of extended-release morphine sulfate with a sequestered naltrexone core (MS-sNT). Taken as directed, morphine provides analgesia while naltrexone remains sequestered; if tampered with b...
متن کاملAnother case of extended-release bupropion-induced seizure.
To the Editor: I read with great interest the report on grand mal seizures being induced by extended-release bupropion hydrochloride (bupropion ER), written by David J. Rissmiller, DO, and Thomas Campo, DO,1 in the October 2007 issue of JAOA—The Journal of the American Osteopathic Association. I too have observed this association between bupropion ER and grand mal seizures. In treating a 42-yea...
متن کاملTreating Opioid Dependence With Injectable Extended-Release Naltrexone (XR-NTX)
OBJECTIVES Once-monthly intramuscular extended-release naltrexone (XR-NTX) has demonstrated efficacy for the prevention of relapse in opioid dependence, providing an alternative to agonist or partial agonist maintenance (ie, methadone and buprenorphine). The question remains, for whom is this unique treatment most efficacious and can patient-treatment matching factors be identified? METHODS A...
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ژورنال
عنوان ژورنال: JAMA
سال: 2015
ISSN: 0098-7484
DOI: 10.1001/jama.2015.1617