Nanobody-Based Probes for Subcellular Protein Identification and Visualization

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

mEosFP-based green-to-red photoconvertible subcellular probes for plants.

Photoconvertible fluorescent proteins (FPs) are recent additions to the biologists' toolbox for understanding the living cell. Like green fluorescent protein (GFP), monomeric EosFP is bright green in color but is efficiently photoconverted into a red fluorescent form using a mild violet-blue excitation. Here, we report mEosFP-based probes that localize to the cytosol, plasma membrane invaginati...

متن کامل

COMPARTMENTS: unification and visualization of protein subcellular localization evidence

Information on protein subcellular localization is important to understand the cellular functions of proteins. Currently, such information is manually curated from the literature, obtained from high-throughput microscopy-based screens and predicted from primary sequence. To get a comprehensive view of the localization of a protein, it is thus necessary to consult multiple databases and predicti...

متن کامل

Evaluation and Visualization of Pathway Efficiency based on Subcellular Protein Localizations

For visualizing and analyzing subcellular localizations, we presented the subcellular localization charts in 2013 [1]. After a concrete localization scenario is found, it can be visualized in the context of a virtual cell environment. To acquire the heterogeneous localization data, two information sources where combined with the CELLmicrocosmos 4.2 PathwayIntegration, DAWIS-M.D. and ANDCell [2]...

متن کامل

Nanobody Based Dual Specific CARs

Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas. However, targeting a single antigen may not be sufficient, and relapse due to the emergence of antigen negative leukemic cells may occur. A potential strategy to counter the outgrowth of antigen escape va...

متن کامل

Flow Surface Probes for Vector Field Visualization

We present a technique called ow surface probes for interactive visualization of 3D steady vector elds. The user places in the ow eld an arbitrarily-shaped seed surface, which is then deformed over time by the local or global 3D vector eld, producing an animation sequence. This sequence and individual frames are used to probe the behavior of the ow eld.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Cellular Neuroscience

سال: 2020

ISSN: 1662-5102

DOI: 10.3389/fncel.2020.573278