Nanoengineered Surfaces Enhance Drug Loading and Adhesion

Condensation Heat Transfer on Nanoengineered Surfaces

This thesis presents a series of three related studies with the aim of developing a surface that promotes robust dropwise condensation. Due to their remarkably low droplet adhesion, superhydrophobic surfaces were investigated for application to dropwise condensation. Although precise model superhydrophobic surfaces were necessary to gain insight into these phenomena, it was recognized that wide...

Toward generating low-friction nanoengineered surfaces with liquid-vapor interfaces.

Using molecular dynamics (MD), we investigate the importance of liquid-vapor interface topography in designing low-friction nanoengineered superhydrophobic surfaces. Shear flow is simulated on patterned surfaces. The relationship between the effective slip length and bubble meniscus curvature is attained by generating entrapped bubbles with large protrusion angles on patterned surfaces with nan...

Nanoengineered surfaces for microfluidic-based thermal management devices

Microfluidic systems offer compact and efficient thermal management strategies. In this work, we investigate novel nanostructured surfaces to control fluidic behavior and enhance heat dissipation in microfluidic systems. We fabricated silicon nanopillars ranging from 200 nm to 800 nm in diameter and heights of approximately 5 μm. In the presence of notches on the pillars, the liquid separates i...

Enhanced osteoblast adhesion to drug-coated anodized nanotubular titanium surfaces

Current orthopedic implants have functional lifetimes of only 10-15 years due to a variety of reasons including infection, extensive inflammation, and overall poor osseointegration (or a lack of prolonged bonding of the implant to juxtaposed bone). To improve properties of titanium for orthopedic applications, this study anodized and subsequently coated titanium with drugs known to reduce infec...

TITLE : Nanoengineered Drug Combinations for Breast Cancer Treatment