Nanomaterials Exhibiting Enzyme-Like Properties (Nanozymes): Current Advances and Future Perspectives

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes.

Over the past few decades, researchers have established artificial enzymes as highly stable and low-cost alternatives to natural enzymes in a wide range of applications. A variety of materials including cyclodextrins, metal complexes, porphyrins, polymers, dendrimers and biomolecules have been extensively explored to mimic the structures and functions of naturally occurring enzymes. Recently, s...

Down Syndrome: Current Status, Challenges and Future Perspectives

Down syndrome (DS) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. It is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. Although the syndrome had been described thousands of years before, it was named after John Langdon Down who described ...

Modeling Tumorigenesis in Drosophila: Current Advances and Future Perspectives

Enzyme-like activity of nanomaterials.

Due to possessing an extremely small size and a large surface area per unit of volume, nanomaterials have specific characteristic physical, chemical, photochemical, and biological properties that are very useful in many new applications. Nanoparticles' catalytic activity and intrinsic ability in generating or scavenging reactive oxygen species in general can be used to mimic the catalytic activ...

Pharmacodynamic properties of antiplatelet agents: current knowledge and future perspectives.

Platelets play an important role in atherothrombotic disease. The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A(2) synthesis, ADP-mediated signaling, and glycoprotein IIb/IIIa-mediated platelet aggregation. The improvement of our understanding on the pharmacokinetic and pharmacodynamic characteristics of these drugs enables the tailoring ...