Near-fatal systemic oxygen embolism due to wound irrigation with hydrogen peroxide

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Near-fatal systemic oxygen embolism due to wound irrigation with hydrogen peroxide.

Shock and coma developed suddenly in a 54-year-old male undergoing irrigation of an infected and fistulous herniorrhaphy wound with 3% hydrogen peroxide (H202). Marked ST elevation was seen in almost all electrocardiogram (ECG) leads. Within one hour the patient recovered completely, and the ECG returned to normal. The mechanism of this occurrence was most likely widespread embolization of oxyg...

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Oxygen embolism due to hydrogen peroxide irrigation during cervical spinal surgery.

Hydrogen peroxide is used to cleanse and irrigate wounds. As it decomposes immediately into water and oxygen on contact with organic tissue, it is usually regarded as a safe agent. We report a case of oxygen embolism associated with hydrogen peroxide irrigation of the surgical field during anterior fusion of the cervical vertebrae. It was accompanied by precipitous hypotension and decrease in p...

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Oxygen embolism after hydrogen peroxide irrigation of a vulvar abscess.

We report a case of venous oxygen embolism in a 33-yr-old healthy woman after irrigation of a vulvar abscess with 25 ml of 3% hydrogen peroxide. Venous oxygen embolism was diagnosed by the development of sudden hypoxia associated with a decrease in end-tidal carbon dioxide concentration from 5.3 kPa to 3.2 kPa, and a 'mill-wheel' sound on cardiac auscultation soon after injection of the solutio...

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Hydrogen Peroxide Wound Irrigation in Orthopaedic Surgery

As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm. Hydrogen peroxide has been used medically for almost a century, but its applications in orthopaedic surgery have yet to be fully determined. The basic science and clinical research on the antiseptic efficacy of h...

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Massive Cerebral Gas Embolism under Discectomy due to Hydrogen Peroxide Irrigation

Massive cerebral and spinal gas embolism occurs rarely as a complication of discectomy. We report a 54-year-old female who had undergone a discectomy (L3/4 and L4/5) under epidural anesthesia in a local hospital developed multiple massive gas embolisms. At closure, surgeons irrigated the incision wound with hydrogen peroxide. Soon after the irrigation, the patient suddenly developed tachycardia...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1982

ISSN: 0032-5473

DOI: 10.1136/pgmj.58.681.448