Neural Stimulation of Release of Renin

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Neural stimulation of release of renin.

Increased vasomotor discharge induced by bleeding caused renal release of renin in anesthetized dogs whether or not there was measurable change in either arterial pressure or total renal blood flow. Release of renin was prevented by ganglion blockade or local anesthesia of the renal nerves. Hemorrhage-induced release of renin occurred more consistently in dogs fed a low-sodium diet than in thos...

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Stimulation of renin release by intrarenal calcium infusion.

The effects of intrarenal infusions of calcium gluconate (10 and 100 micrograms Ca/kg/min) on renin secretion were studied in anesthetized mongrel dogs. In one group, the two doses of calcium were infused for 30 minutes each (1 ml/min). In a second group, the same doses were administered 30 minutes after the start of infusion of prostaglandin synthesis inhibitors (indomethacin 10 micrograms/kg/...

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Diazoxide-induced stimulation of renin release in renal vein renin sampling.

1. The acute effect of diazoxide (150-300 mg, intravenously) on renal venous renin has been evaluated in forty-four patients with suspected renal hypertension. 2. In twenty-seven studies which showed no lateralization, diazoxide raised the mean peripheral renin to 175% of control (P less than 0-05) but the renal vein renin ratio showed an insignificant change (1-15 to 1-21). 3. In seventeen stu...

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Renin and aldosterone release during sympathetic stimulation in tetraplegia.

1. The effect of endogenous sympathetic stimulation (induced by urinary bladder stimulation) and intravenous infusion of noradrenaline and isoprenaline on blood pressure, heart rate and levels of plasma renin activity and plasma aldosterone were studied in six tetraplegic patients. Data from infusion studies were compared with data from six normal subjects studied in an identical manner. 2. Bla...

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Increased renin release evoked by mesencephalic stimulation in the dog.

T HERE has been a growing body of evidences that renal pressor system and sympathetic nervous system relate each other. Indeed many investigators have recently elucidated the role of renal nerve and catecholamines in renin secretion.1)-6) But the responses of renin secretion to the central nervous system activity have not yet been reported, though it seems to play the most important role in the...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1966

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.19.4.851