Neurodegeneration, Heterochromatin, and Double-Stranded RNA

Double-stranded RNA poses puzzle.

Microglia Recognize Double-Stranded RNA

double-stranded rna viral infection in tehran trichomonas vaginalis isolates.

background : trichomonas vaginalis is a pathogenic protozoon and may be contaminated with dsrna virus called trichomonas vaginalis virus (tvv). the viral infection is an important factor for its patho-genesis and sensitivity to metronidazole. the presence of tvv is associated with qualitative and quantitative expression of cysteine proteinases and surface immunogenic; p270. the purpose of this ...

Interferon, double-stranded RNA, and protein phosphorylation.

We reported earlier that the addition of double-stranded RNA and ATP increases the endonuclease activity more in an extract of Ehrlich ascites tumor cells which have been treated with an interferon preparation than in a comparable extract from control cells. We report here that the addition of double-stranded RNA to an extract from Ehrlich ascites tumor cells which have been treated with an int...

RNA interference and double-stranded-RNA-activated pathways.

RNAi (RNA interference) has become a powerful tool to determine gene function. Different methods of expressing the short ds (double-stranded) RNA intermediates required for interference in mammalian systems have been developed, including the introduction of si (short interfering) RNAs by direct transfection or driven from transfected plasmids or lentiviral vectors encoding sh (short hairpin) RN...