Neuroendocrine Self-Control: Dendritic Release of Vasopressin
نویسندگان
چکیده
منابع مشابه
Neuroendocrine self-control: dendritic release of vasopressin.
The past two decades have produced many new insights into the cellular mechanisms that regulate the firing patterns of hormone-secreting magnocellular neurons in the supraoptic and paraventricular nuclei of the hypothalamus. These firing patterns determine how much vasopressin or oxytocin is released into the systemic circulation. One such insight is the realization that these peptides are rele...
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While the existence of an osmotic control for vasopressin (AVP) release has been long recognized, development of a sensitive immunoassay has allowed for better understanding of factors affecting the threshold and sensitivity of AVP release. Individual variation, genetic, environmental, and species differences, and the nature of the solute providing the osmotic stimuli can significantly affect t...
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Hypothalamic magnocellular neurons release vasopressin and oxytocin not only from their axon terminals into the blood, but also from their somata and dendrites into the extracellular space of the brain, and this can be regulated independently. Differential release of neurotransmitters from different compartments of a single neuron requires subtle regulatory mechanisms. Somato-dendritic, but not...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2007
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2006-1531