Neuronal activity up-regulates astroglial gene expression.
نویسندگان
چکیده
منابع مشابه
Neuronal activity up-regulates astroglial gene expression.
Neuronal gene expression is known to be modulated by functional activity. This modulation is thought to play a key role in determining the differentiation of developing neurons and regulating the operation of mature neurons. Here we describe a regulation of astroglial gene expression by neuronal activity. We report that intense neuronal activity (electrically induced seizures) in rat hippocampu...
متن کاملHyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD...
متن کاملRhizophagus irregularis regulates antioxidant activity and gene expression under cadmium toxicity in Medicago sativa
Cadmium (Cd) is a phytotoxic heavy metal (HM) that can induce generation of reactive oxygen species (ROS). Arbuscular mycorrhizal fungi (AMF) are considered as bio-ameliorators that help to mitigate HM-derived oxidative stress. The objective of this study was to assess AM fungus Rhizophagus irregularis on changes in enzymatic activity and transcription of antioxidants of Medicago sativa to Cd s...
متن کاملAstroglial gap junctions shape neuronal network activity
Astrocytes, the third element of the tripartite synapse, are active players in neurotransmission. Up to now, their involvement in neuronal functions has primarily been investigated at the single cell level. However, a key property of astrocytes is that they communicate via extensive networks formed by gap junction channels. Recently, we have shown that this networking modulates the moment to mo...
متن کاملNeuronal Activity Regulates Hippocampal miRNA Expression
Neuronal activity regulates a broad range of processes in the hippocampus, including the precise regulation of translation. Disruptions in proper translational control in the nervous system are associated with a variety of disorders that fall in the autistic spectrum. MicroRNA (miRNA) represent a relatively recently discovered player in the regulation of translation in the nervous system. We ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1991
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.88.15.6819