Neuroprotective effects of 4,5-dimethoxypyrocatechol isolated from Cynanchum paniculatum on HT22 cells
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چکیده
منابع مشابه
C21 steroidal glycosides from the roots of Cynanchum paniculatum.
As a part of our continuing research for bioactive constituents from Cynanchum plants, four new C21 steroidal glycosides, cynapanoside D-G (1-4), together with six known compounds (5-10) were isolated from the roots of Cynanchum paniculatum (Bge.) Kitag. Their structures were elucidated on the basis of 1D- and 2D-NMR spectroscopic data as well as HR-ESI-MS analysis. Compound 8 exhibited potent ...
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Two new steroidal saponins, cynanside A (1) and B (2) were isolated together with three known compounds (3-5) from the roots of Cynanchum paniculatum (Bunge) Kitag. The structures of 1 and 2 were elucidated on the basis of spectroscopic analyses, including extensive 2D NMR and acid hydrolysis. We evaluated the cytotoxicity of isolates (1-5) against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines...
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BACKGROUND Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy. MATERIAL AND METHODS The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done w...
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Solanum paniculatum L. is a plant species widespread throughout tropical America, especially in the Brazilian Cerrado region. It is used in Brazil for culinary purposes and in folk medicine to treat liver and gastric dysfunctions, as well as hangovers. Previous studies with S. paniculatum ethanolic leaf extract or ethanolic fruit extract demonstrated that they have no genotoxic activity neither...
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ژورنال
عنوان ژورنال: Pharmacognosy Magazine
سال: 2014
ISSN: 0973-1296
DOI: 10.4103/0973-1296.131028