New Developments in Mass Chromatography-spectrometry Research for Forensic Toxicology
نویسندگان
چکیده
منابع مشابه
Liquid chromatography-mass spectrometry in forensic toxicology.
Liquid chromatography-mass spectrometry has evolved from a topic of mainly research interest into a routinely usable tool in various application fields. With the advent of new ionization approaches, especially atmospheric pressure, the technique has established itself firmly in many areas of research. Although many applications prove that LC-MS is a valuable complementary analytical tool to GC-...
متن کاملLibrary Search-based Drug Analysis in Forensic Toxicology by Liquid Chromatography–mass Spectrometry
Liquid chromatography–mass spectrometry (LC–MS) with electrospray (ES) ionization in the positive ion mode was applied to drug analysis in forensic toxicology. Several types of screening and confirmation strategies were developed, based essentially on searching of comprehensive MS libraries and databases that were created in-house for the purpose. Two spectral libraries, both containing spectra...
متن کاملCurrent role of liquid chromatography-mass spectrometry in clinical and forensic toxicology.
This paper reviews multi-analyte single-stage and tandem liquid chromatography-mass spectrometry (LC-MS) procedures using different mass analyzers (quadrupole, ion trap, time-of-flight) for screening, identification, and/or quantification of drugs, poisons, and/or their metabolites in blood, plasma, serum, or urine published after 2004. Basic information about the biosample assayed, work-up, LC...
متن کاملLiquid chromatography – mass spectrometry in forensic and clinical 1 toxicology Hans
This paper reviews liquid chromatographic–mass spectrometric (LC–MS) procedures for the identification and/or quantification of drugs of abuse, therapeutic drugs, poisons and/or their metabolites in biosamples (whole blood, plasma, serum, urine, cerebrospinal fluid, vitreous humor, liver or hair) of humans or animals (cattle, dog, horse, mouse, pig or rat). Papers published from 1995 to early 1...
متن کاملProgress of liquid chromatography-mass spectrometry in clinical and forensic toxicology.
The use of liquid chromatography-mass spectrometry (LC-MS) has recently exploded in various analytic fields, including toxicology and therapeutic drug monitoring (although still far behind pharmacokinetics). There is no doubt that LC-MS is currently competing with gas chromatography (GC)-MS for the status of the reference analytic technique in toxicology. This review presents, for the nonspecia...
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ژورنال
عنوان ژورنال: Nihon Ika Daigaku Igakkai Zasshi
سال: 2011
ISSN: 1349-8975,1880-2877
DOI: 10.1272/manms.7.8