New Insight into the Hypercoagulability of Cushing’s Syndrome

New insight into the hypercoagulability of Cushing's syndrome.

BACKGROUND Hypercoagulability and a tendency for thromboembolic complications are reported in Cushing's syndrome (CS). The hypercoagulability is due mainly to the cortisol-induced increase in von Willebrand factor (VWF) and factor VIII. This is not a constant feature of CS, however; it depends on particular single nucleotide polymorphism (SNP) haplotypes in the VWF gene promoter: haplotype 1 (-...

Mitophagy: New Insight into the Cardiovascular Aging  

New Insight into the Relation between Adiponectin and Diabetes

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

New insight into the clinico-histomycological aspects of onychomycosis and a review of the literature

Background: Onychomycosis (OM) is the infection of nails caused by a variety of fungi. As systemic antifungal treatment is necessary in the majority of patients, appropriate diagnostic techniques are important to ensure a correct diagnosis and treatment. Objective: This study was carried out to evaluate the clinical, mycological, and histological aspects of onychomycosis in detail. Methods: A c...

A new insight into the management of myofascial pain syndrome

Myofascial pain syndrome (MPS) is a musculoskeletal disorder which is characterized by pain, muscle spasms, and muscle tenderness, as well as a limited range of motion, weakness, and rarely, autonomous dysfunction. Management includes exercise programs in particular, and many other invasive and non-invasive therapies, depending on the clinical status of the patient. The main options include med...