New trends of animal cell engineering.(1).1.Development of animal cell engineering.

Therapeutic Potential of Cord Blood Stem Cell in Brain Damage of an Animal Model

Purpose: At the present time the role of stem cells and its therapeutic effects is well known. Human or animal (bone marrow or cord blood) stem cells in stem cell therapy are a promising attempt to improve the recovery after post embryonic injuries. Materials and Methods: The present study was carried out on young Wistar rats. At first, cord blood stem cells (CBSCs) were isolated, and labeled w...

Toward Animal Cell Culture

Animal cell hydraulics.

Water is the dominant ingredient of cells and its dynamics are crucial to life. We and others have suggested a physical picture of the cell as a soft, fluid-infiltrated sponge, surrounded by a water-permeable barrier. To understand water movements in an animal cell, we imposed an external, inhomogeneous osmotic stress on cultured cancer cells. This forced water through the membrane on one side,...

Ambivalent Effects of Atorvastatin on Angiogenesis, Epidermal Cell Proliferation and Tumorgenesis in Animal Models

Background: A growing body of preclinical data indicates that statins may possess antineoplastic properties however, some studies have raised the possibility that statins may also have carcinogenic potential. Methods: An air pouch model was used for angiogenesis. Single or multiple applications of croton oil on the back of Swiss albino mice with or without initiation by dimethylbenz(a)antherace...

New peptide-based and animal-free coatings for animal cell culture in bioreactors

Background Anchorage dependent cells require an appropriate extracellular matrix for their survival, migration, proliferation, phenotyping and/or differentiation [1-3]. These cells interact with extracellular matrix proteins, primarily through integrins, which induces focal adhesion contacts assembly and activation of signalling pathways that regulate diverse cellular processes [4]. Culture sup...