Next Effort in Cholinesterases Biosensors

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Next Effort in Cholinesterases Biosensors

Acetyl cholinesterase (AChE) and butyryl cholinesterase (BChE) are two known enzymes in the body with ability to hydrolyze acetylcholine. While AChE plays crucial role in acetylcholine mediated neurotransmission, BChE is secreted from livers to plasma and biological role of the enzyme is not fully understood [1]. The both cholinesterases are very sensitive to inhibition by nerve agents such as ...

متن کامل

Optical biosensors: where next and how soon?

From a direct comparison of the technical benefits of labelled reporter assays with the benefits of label-free assays, label-free appears to have significant advantages. Faster assay development times; accurate, high information content data; and less interference from labels. However, optical label-free platforms have not yet made a major impact in the drug discovery technology markets; are of...

متن کامل

Cholinesterases in human skin.

This study concerns the distribution of cholinesterases in human skin. Previous work on this subject was published last year by Hurley, Shelley and Koelle (1) These authors used a method originated by Koelle (2, 3). In Koelle's method, acetyithiocholine and butyryithiocholine are used as substrates. It is assumed that acetyithiocholine is split by specific acetyicholinesterase as well as by non...

متن کامل

The cholinesterases.

In 1914 Sir Henry Dale (1) suggested that an enzyme which degrades the esters of choline played a role in neurotransmission within the autonomic and somatic motor nervous systems and that this enzyme, acetylcholinesterase, was the target of action of the drug, physostigmine (eserine). In the intervening 75 years, inhibition of the enzyme has been used to augment both the nicotinic and muscarini...

متن کامل

MoS₂ field-effect transistor for next-generation label-free biosensors.

Biosensors based on field-effect transistors (FETs) have attracted much attention, as they offer rapid, inexpensive, and label-free detection. While the low sensitivity of FET biosensors based on bulk 3D structures has been overcome by using 1D structures (nanotubes/nanowires), the latter face severe fabrication challenges, impairing their practical applications. In this paper, we introduce and...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Biosensors & Bioelectronics

سال: 2015

ISSN: 2155-6210

DOI: 10.4172/2155-6210.1000161