Nitric oxide synthesis in patients with infective gastroenteritis

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Nitric oxide synthesis in patients with infective gastroenteritis.

BACKGROUND There is evidence that endogenous nitrate synthesis is notably increased in patients with infective gastroenteritis. AIMS To determine whether this is due to nitric oxide (NO) production via the L-arginine/NO pathway. METHODS Seven male patients with community acquired bacterial gastroenteritis and 15 healthy male volunteers participated in this study. All patients had stool cult...

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Increased nitric oxide in infective gastroenteritis.

Nitric oxide (NO) production is increased in several inflammatory disorders, although the role of this gas is not clear. The purpose of this study was to determine whether luminal NO in the intestine is increased in infective gastroenteritis. Rectal gas was sampled in 17 patients with gastroenteritis and 10 healthy volunteers, with balloon catheters made of 100% silicone and analyzed for NO by ...

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Monitoring of Serum Nitric oxide in Patients with Acute Leukemia

Nitric oxide (NO) is a molecule required for many physiological functions, produced from L-arginine by NO synthases (NOS). It is a free radical, producing many reactive intermediates that account for its bioactivity. Sustained induction of the inducible form of NOS (iNOS) in chronic inflammation may be mutagenic, through NO-mediated DNA damage or hindrance to DNA repair, and thus potentially ca...

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Monitoring of Serum Nitric oxide in Patients with Acute Leukemia

Nitric oxide (NO) is a molecule required for many physiological functions, produced from L-arginine by NO synthases (NOS). It is a free radical, producing many reactive intermediates that account for its bioactivity. Sustained induction of the inducible form of NOS (iNOS) in chronic inflammation may be mutagenic, through NO-mediated DNA damage or hindrance to DNA repair, and thus potentially ca...

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ژورنال

عنوان ژورنال: Gut

سال: 1999

ISSN: 0017-5749,1468-3288

DOI: 10.1136/gut.45.3.355