NMO Antibody–Positive Recurrent Optic Neuritis Without Clear Evidence of Transverse Myelitis
نویسندگان
چکیده
منابع مشابه
The expanded spectrum of neuromyelitis optica: evidences for a new definition.
Neuromyelitis optica (NMO) has been traditionally described as the association of recurrent or bilateral optic neuritis and longitudinally extensive transverse myelitis (LETM). Identification of aquaporin-4 antibody (AQP4-IgG) has deeply changed the concept of NMO. A spectrum of NMO disorders (NMOSD) has been formulated comprising conditions which include both AQP4-IgG seropositivity and one of...
متن کاملTransverse myelitis and bilateral optic neuritis in a patient with systemic lupus erythematosus.
Optic neuromyelitis (ONM)orDevic’s syndrome is an inflammatory demyelinating central nervous system (CNS) disease, defined by the presence of optic neuritis, transverse myelitis affecting 3 or more spinal segments and seropositivity for antibodies directed against aquaporin4of astrocytes (NMO-IgG), in theabsenceof signs of brain lesions suggestive of multiple sclerosis (MS).1 We report the case...
متن کامل[Clinical overview of neuromyelitis optica].
Neuromyelitis optica (NMO) is a condition characterized by attacks of severe bilateral optic neuritis and myelitis. Historically, the prototypic syndrome was diagnosed only when these symptoms occurred nearly simultaneously as a monophasic illness. However, a contemporary view acknowledges that most commonly this condition is a relapsing disorder characterized by recurrent attacks, usually of u...
متن کاملSystemic Lupus Erythematosus with Neuromyelitis Optica
Systemic lupus erythematosus (SLE) is an autoimmune disease that can have detrimental effects on many different systems in the body, including the central nervous system. Neuropsychiatric SLE (NPSLE) refers to several different neurological and/or behavioral clinical syndromes, and has been reported as having a prevalence rate of approximately 30−40%, while manifestation of myelitis or optic ne...
متن کاملTransverse myelitis spectrum disorders.
Acute transverse myelitis (ATM) is an inflammatory demyelinating disorder that affects the spinal cord focally resulting in motor sensory and autonomic dysfunction. Establishing the diagnosis of ATM is not as difficult as determining the possible etiology. There is a difference in the perception of ATM seen in the West as compared to developing countries. In the West multiple sclerosis (MS) is ...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2008
ISSN: 0003-9950
DOI: 10.1001/archopht.126.4.566