Nomograms predicting extra- and early intrahepatic recurrence after hepatic resection of hepatocellular carcinoma

Background Extrahepatic recurrence and early intrahepatic of hepatocellular carcinoma after hepatic resection are indicative poor prognoses. We aimed to develop nomograms predict extrahepatic resection. Methods The participants this study were 1,206 patients who underwent initial curative for carcinoma. Multivariate logistic regression analyses using the Akaike information criterion used construct (within 1 year surgery) at first sites Performance each nomogram was evaluated by calibration plots with bootstrapping. Results identified in 95 (7.9%) 296 (24.5%). Three predictive factors, ?-fetoprotein >200 ng/mL, tumor size (3–5 cm or >5 vs ?3 cm), image-diagnosed venous invasion computed tomography, adopted final model a concordance index 0.75. Tumor 2 additional predictors (ie, multiple tumors portal invasion) 0.67. showed good agreement between predictions actual observations recurrence, respectively. Conclusion have developed reliable These useful diagnostic prediction could guide surgeon’s selection treatment strategies patients.